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FcγRIII activation is different in CD16+ cytotoxic T lymphocytes and natural killer cells

✍ Scribed by Peter Uciechowski; J. Engelbert Gessner; Ralf Schindler; Reinhold E. Schmidt


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
416 KB
Volume
22
Category
Article
ISSN
0014-2980

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## Activation of natural killer cells via the FcyRIII (CD16) requires initial tyrosine phosphorylation* Triggering of the FcyRIII (CD16) on natural killer (NK) cells by monoclonal antibodies or antibody-coated target cells stimulates a rapid phospholipase C (PLC)-mediated hydrolysis of inositol ph