FcRL5 as a Target of Antibody-Drug Conjugates for the Treatment of Multiple Myeloma
β Scribed by Elkins, K.; Zheng, B.; Go, M.; Slaga, D.; Du, C.; Scales, S. J.; Yu, S.-F.; McBride, J.; de Tute, R.; Rawstron, A.; Jack, A. S.; Ebens, A.; Polson, A. G.
- Book ID
- 115513775
- Publisher
- American Association for Cancer Research
- Year
- 2012
- Tongue
- English
- Weight
- 867 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1535-7163
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This volume gathers the leading research on antibody-drug conjugates and immunotoxins. Following a rigorous overview, the volume delves into focused sections on all aspects of ADCs and ITs from clinical development through to targeted therapeutic applications and the latest technologies.
Monoclonal antibodies directed to tumor-associated antigens have been chemically conjugated to drugs with different mechanisms of action and different levels of potency. Monoclonal-antibody-directed drug delivery has the potential to both improve efficacy and reduce systemic toxicity. Several immuno