FC035 A comparison of two formulations of cyclosporin in severe psoriasis
β Scribed by J. Berth-Jones; T. Ruzicka
- Book ID
- 118604319
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 123 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0926-9959
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
This study compared the efficacy, safety and optimal dose of two formulations of cyclosporin, Sandimmun and Neoral, in patients with severe, chronic plaque-type psoriasis. Patients were randomized on a 1:1 basis to 24 weeks of treatment with Neoral (n = 152) or Sandimmun (n = 157). The starting dose
Eight patients whose severe psoriasis was treated with long-term cyclosporin (range 2-11 years; mean 7.6 years) were changed to mycophenolate mofetil (MMF), because of nephrotoxicity in seven and hypertension and lack of efficacy in one. In five patients psoriasis control significantly deteriorated