## Abstract Resistance to anticancer drugs is a major obstacle preventing effective treatment of disseminated cancers. Understanding the molecular basis to chemoresistance is likely to provide better treatment. Cell lines resistant to cisplatin or 5βfluorouracil (5βFU) were established from human g
Fatty acids decrease catalase activity in human leukaemia cell lines
β Scribed by Anna K. Azevedo-Martins; R. Curi
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 176 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0263-6484
- DOI
- 10.1002/cbf.1404
No coin nor oath required. For personal study only.
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## Methods Mitoxantrone was purchased from Lederle (France) and doxorubicin from Dakota (France). Stock solutions stored at Οͺ20Β°C (9 Ο« 10 Οͺ4 M for doxorubicin and 4 Ο« 10 Οͺ3 M for mitoxantrone) and dilutions of doxorubicin and mitoxantrone were freshly prepared in physiological saline solution, NaC