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Fatal reactivation of hepatitis B virus mutant following cytotoxic treatment

✍ Scribed by Jean-Charles Duclos-Vallee; Pierre Laurent-Puig; Marie-Anne Loriot; Catherine Buffet; David Malka; Gilles Pelletier; Patrick Marcellin; Serge Erlinger; Jean-Pierre Etienne

Book ID: 118566478
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 105 KB
Volume: 21
Category: Article
ISSN: 0168-8278
DOI: 10.1016/s0168-8278(05)80641-5

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## BACKGROUND. A point mutation from G to A at nucleotide (nt) 1896 of the precore region of hepatitis B virus (HBV) DNA has been shown to be associated with fulminant and severe hepatitis. Further studies have suggested that this point mutation, together with additional mutations in the precore p