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Antineoplastics: reactivation of precore mutant hepatitis B virus infection

Book ID
120864524
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2002
Weight
120 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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## BACKGROUND. A point mutation from G to A at nucleotide (nt) 1896 of the precore region of hepatitis B virus (HBV) DNA has been shown to be associated with fulminant and severe hepatitis. Further studies have suggested that this point mutation, together with additional mutations in the precore p