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FAT10 modifies p53 and upregulates its transcriptional activity

✍ Scribed by Tianwei Li; Rasa Santockyte; Shiqin Yu; Rong-Fong Shen; Ephrem Tekle; Caroline G.L. Lee; David C.H. Yang; P. Boon Chock

Book ID: 116178834
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 731 KB
Volume: 509
Category: Article
ISSN: 0003-9861
DOI: 10.1016/j.abb.2011.02.017

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## Abstract In response to various stresses, p53 is rapidly activated and transcriptionally regulates a number of target genes by which p53 modulates a variety of cellular activities. The transcriptional activity of p53 is delicately regulated by a plethora of cellular factors, independently or syn