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Fast protein folding on downhill energy landscape

✍ Scribed by Andrea Cavalli; Urs Haberthür; Emanuele Paci; Amedeo Caflisch


Book ID
119824340
Publisher
Cold Spring Harbor Laboratory Press
Year
2003
Tongue
English
Weight
86 KB
Volume
12
Category
Article
ISSN
0961-8368

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## Abstract The Notch ankyrin domain is a repeat protein whose folding has been characterized through equilibrium and kinetic measurements. In previous work, equilibrium folding free energies of truncated constructs were used to generate an experimentally determined folding energy landscape (Mello