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Fast Production of Highly Reactive No-Carrier-Added [18F]Fluoride for the Labeling of Radiopharmaceuticals

✍ Scribed by Christian F. Lemaire; Joël J. Aerts; Samuel Voccia; Lionel C. Libert; Frédéric Mercier; David Goblet; Alain R. Plenevaux; André J. Luxen


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
423 KB
Volume
49
Category
Article
ISSN
0044-8249

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To improve the accessibility of [18F]arylfluorides a method is presented using the decomposition of aromatic diazonium salts in the presence of [18F]fluoride. Several p-toluidyldiazonium salts have been synthesized and decomposed in the presence of fluoride. The most useful salt, ptoluidyldiazonium-