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Fast LC–MS Electrospray Ionization for the Quantification of Digoxin in Human Plasma and Its Application to Bioequivalence Studies

✍ Scribed by Leonardo S. Teixeira; Iram M. Mundim; Weidson C. Souza; Douglas R. Ramos; Karine B. Bellorio; Fernanda G. Marques; Kênnia R. Rezende

Book ID: 111683229
Publisher: Springer
Year: 2009
Tongue: English
Weight: 501 KB
Volume: 69
Category: Article
ISSN: 0009-5893
DOI: 10.1365/s10337-009-1014-2

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## Abstract A novel High Performance Liquid Chromatography — electrospray mass spectrometric method has been developed for the estimation of Ursodiol (Ursodeoxycholic acid)‐a bile acid, in human plasma using Ornidazole as internal standard. The methodology involved solid phase extraction of the ana