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Electrospray ionization LC-MS/MS validated method for the determination of the active metabolite (R-138727) of prasugrel in human plasma and its application to a bioequivalence study

✍ Scribed by Ojikumar Lukram; Mukund Zarapkar; Chandan Kumar Jha; Shivaji Parmar; Keshav S. Tomar; Amit Hande

Book ID: 112073811
Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 244 KB
Volume: 4
Category: Article
ISSN: 1942-7603
DOI: 10.1002/dta.264

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## Abstract A novel High Performance Liquid Chromatography — electrospray mass spectrometric method has been developed for the estimation of Ursodiol (Ursodeoxycholic acid)‐a bile acid, in human plasma using Ornidazole as internal standard. The methodology involved solid phase extraction of the ana