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Fast imaging of phosphocreatine using a RARE pulse sequence

✍ Scribed by Robert L. Greenman; Mark A. Elliott; Krista Vandenborne; Mitchell D. Schnall; Robert E. Lenkinski

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
461 KB
Volume
39
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

A technique is described for acquiring phosphocreatine (PCr) images of skeletal muscle using a rapid acquisition with relaxation enhancement (RARE) pulse sequence. All of the phosphorus metabolites other than PCr are forced to dephase within the first few echoes, whereas the Carr‐Purcell Mei‐boom‐Gill (CPMG) pulse sequence maintains a high PCr signal long enough to acquire 64 echoes in a single shot. Axial PCr images of a human forearm with a signal‐to‐noise ratio of 9 were acquired in 2 min. The effect of the refocusing pulse section profile on the ratio of desired to undesired metabolite signal is demonstrated.

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