Fast CT-PRESS-based spiral chemical shift imaging at 3 Tesla

✍ Scribed by Dirk Mayer; Dong-Hyun Kim; Elfar Adalsteinsson; Daniel M. Spielman

• Publisher: John Wiley and Sons
• Year: 2006
• Tongue: English
• Weight: 293 KB
• Volume: 55
• Category: Article
• ISSN: 0740-3194
• DOI: 10.1002/mrm.20853

✦ Synopsis

Abstract

A new sequence is presented that combines constant‐time point‐resolved spectroscopy (CT‐PRESS) with fast spiral chemical shift imaging. It allows the acquisition of multivoxel spectra without line splitting with a minimum total measurement time of less than 5 min for a field of view of 24 cm and a nominal 1.5 × 1.5‐cm^2^ in‐plane resolution. Measurements were performed with 17 CS encoding steps in t~1~ (Δ__t__~1~ = 12.8 ms) and an average echo time of 151 ms, which was determined by simulating the CT‐PRESS experiment for the spin systems of glutamate (Glu) and myo‐inositol (mI). Signals from N‐acetyl‐aspartate, total creatine, choline‐containing compounds (Cho), Glu, and mI were detected in a healthy volunteer with no or only minor baseline distortions within 14 min on a 3 T MR scanner. Magn Reson Med, 2006. © 2006 Wiley‐Liss, Inc.