Three glutathione conjugates of acetaminophen were characterized by fast atom bombardmentlmass spectrometry (FABlMS) and fast atom bombardmentlmass spectrometryhass spectrometry (FABlMSlMS). The conjugates, 3-(glutathion-S-yl)acetaminophen, 3-(glutathion-S-yl)diacetaminophen and 3-(diglutathion-S-yl
‘Fast atom bombardment’—A rediscovered method for mass spectrometry
✍ Scribed by F. Marcel Devienne; Jean-Claude Roustan
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 708 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1076-5174
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## Abstract The positive and negative fast atom bombrdment spectra of two groups of simple salts have been recorded. The structures of the major ionic species of eight chlorides and five, complex anion, sodium salts have been interpreted and tabulated.
Girard's reagents were used to derivatize ketosteroids and conjugates for analysis by positive ion fast atom bombardment mass spectrometry. Spectra contain an abundant ion corresponding to the cation ( C ' ) of the newly formed ionic derivative (C+A-) and relatively little fragmentation. With deriva