𝔖 Bobbio Scriptorium
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Fast atom bombardment mass spectrometry of insulin, insulin A-chain, insulin B-chain, and glucagon

✍ Scribed by Dominic M. Desiderio; Itsuo Katakuse

Book ID
101757586
Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
436 KB
Volume
11
Category
Article
ISSN
1076-5174

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New methodology for identifying and locating crosslinkages in peptides is described. Pepsin is used to cleave insulin and B-chain dimers of insulin into fragments under conditions which retain the original peptide crosslinkages. After partial separation by HPLC, the peptides are analyzed by fast ato