Fast atom bombardment mass spectrometric analysis of anthracyclines and anthracyclinones
โ Scribed by Chhabil Dass; Ramakrishnan Seshadri; Mervyn Israel; Dominic M. Desiderio
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 742 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1076-5174
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Direct determination of the phospholipid components in adult Drosophila melanogaster was carried out by using fast atom bombardment tandem mass spectrometry (FAB-MS/MS) of both the positive and negative ions. Approximately 50 molecular species were detected, including phosphatidylethanolamine (PE),
Fast atom bombardment (FAB) mass spectra of daunomycin (l), four of its derivatives (2-3, seven bisanthracyclines (6-12) and three mixed-functional daunomycin-acridine derivatives (13-15) are reported. These anthracyclines all exhibited their expected [MH]' ions and peaks corresponding to the fragme