Fast atom bombardment and tandem mass spectrometry of synthetic neuropeptides and their deuterated analogues
β Scribed by S. Waghmare; R.H. Fokkens; N.M.M. Nibbering; F.M. Kaspersen
- Publisher
- Elsevier Science
- Year
- 1988
- Weight
- 58 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0883-2889
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Fast atom bombardment (FAB) combined with tandem mass spectrometry has been used to verify the amino acid sequence in Org 2766 IH-Met(0,)-Glu-His-Phe-D-Lys-PheOH) and its deuterated analogues. It is shown that FAB mass spectrometry in addition to the [M + HJ' ion yields dominantly N-terminal sequenc
We have examined the synthetic N-oxides of five ethylenediamine-type antihistamines using fast atom bombardment (FAB) mass spectrometry and FAB tandem mass spectrometry (MS/MS). Fragmentation of the protonated molecule in the normal and collisionally activated spectra appeared to be characteristic f
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