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Fast 3D functional magnetic resonance imaging at 1.5 T with spiral acquisition

✍ Scribed by Yihong Yang; Gary H. Glover; Peter van Gelderen; Venkata S. Mattay; Attanagoda K. S. Santha; Roy H. Sexton; Nick F. Ramsey; Chrit T. W. Moonen; Daniel R. Weinberger; Joseph A. Frank; Jeff H. Duyn


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
795 KB
Volume
36
Category
Article
ISSN
0740-3194

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✦ Synopsis


Abstract

A new method to perform rapid 3D fMRI in human brain is introduced and evaluated in normal subjects, on a standard clinical scanner at 1.5 Tesla. The method combines a highly stable gradient echo technique with a spiral scan method, to detect brain activation related changes in blood oxygenation with high sensitivity. A motor activation paradigm with a duration of less than 5 min, performed on 10 subjects, consistently showed significant changes in signal intensity in the area of the motor cortex. In all subjects, these changes survived high statistical thresholds.


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