To further investigate the effects of large vessels on the activation maps generated with functional magnetic resonance imaging at 1.5 T, we studied activation of the human visual and motor cortex using a multitude of dedicated FLASH and echo-planar imaging (EPI) scanning techniques. Both slice and
Fast 3D functional magnetic resonance imaging at 1.5 T with spiral acquisition
β Scribed by Yihong Yang; Gary H. Glover; Peter van Gelderen; Venkata S. Mattay; Attanagoda K. S. Santha; Roy H. Sexton; Nick F. Ramsey; Chrit T. W. Moonen; Daniel R. Weinberger; Joseph A. Frank; Jeff H. Duyn
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 795 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0740-3194
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β¦ Synopsis
Abstract
A new method to perform rapid 3D fMRI in human brain is introduced and evaluated in normal subjects, on a standard clinical scanner at 1.5 Tesla. The method combines a highly stable gradient echo technique with a spiral scan method, to detect brain activation related changes in blood oxygenation with high sensitivity. A motor activation paradigm with a duration of less than 5 min, performed on 10 subjects, consistently showed significant changes in signal intensity in the area of the motor cortex. In all subjects, these changes survived high statistical thresholds.
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