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FASLG polymorphism is associated with cancer risk

✍ Scribed by Yan Liu; Qian-Jun Wen; You Yin; Xiao-Tong Lu; Shu-Hong Pu; Huai-Ping Tian; Yue-Fen Lou; Yue-Nian Tang; Xin Jiang; Gen-Sheng Lu; Jian Zhang


Book ID
116430028
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
110 KB
Volume
45
Category
Article
ISSN
0959-8049

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A polymorphism in the CYP17 gene is asso
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CYP17 encodes the enzyme cytochrome P-450c17␣, which mediates both 17␣-hydroxylase and 17,20-lyase in the steroid biosynthesis pathway. A polymorphism in the 5 promoter region of the CYP17 gene has been described. Steroid hormones, especially androgens, are believed to play a key role in the etiolog