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Fasciolicidal potential of proline analogues and proline biosynthesis inhibitors

โœ Scribed by Marion Sheers; Anne J. Campbell; D.J. Beames; S.R. Edwards; R.J. Moore; P.E. Montague


Book ID
115945024
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
708 KB
Volume
12
Category
Article
ISSN
0020-7519

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Bicyclic sulfonamides were synthesized from 4-alkenyl N-alkenylsulfonyl L-prolines using a ring-closure metathesis reaction. Three types of bicyclic sulfonamides varying in the size of the second ring (5,5; 5,6; 5,7) were synthesized. A sulfonamide counterpart of an indolizidinone 2-carboxylic acid