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Fas Is Required for Clonal Selection in Germinal Centers and the Subsequent Establishment of the Memory B Cell Repertoire

✍ Scribed by Yoshimasa Takahashi; Hiromi Ohta; Toshitada Takemori


Book ID
117723025
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
492 KB
Volume
14
Category
Article
ISSN
1074-7613

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## Abstract In this study it has been investigated whether the interaction of antigen and B cell surface immunoglobulin (sIg) is required for full clonal expansion of memory B cells specific for the hapten, p‐azophenyl‐lactoside (lac). Cultures of lac‐primed B cells and keyhole limpet hemocyanin (K