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CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers

✍ Scribed by Huntington, Nicholas D; Xu, Yuekang; Puthalakath, Hamsa; Light, Amanda; Willis, Simon N; Strasser, Andreas; Tarlinton, David M

Book ID: 109923201
Publisher: Nature Publishing Group
Year: 2005
Tongue: English
Weight: 611 KB
Volume: 7
Category: Article
ISSN: 1529-2908
DOI: 10.1038/ni1292

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## Abstract ## Background Differences between human and murine B cells exist at all stages of B‐cell development, including the stage of memory B‐cell formation. B cells in mice are identified with the pan–B‐cell–specific CD45 isoform, B220. In initial studies in humans, it appeared that B220 expr

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