Farnesyltransferase inhibitors in myelodysplastic syndrome
โ Scribed by E. J. Feldman
- Book ID
- 107540139
- Publisher
- Current Science Inc.
- Year
- 2006
- Tongue
- English
- Weight
- 93 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1558-8211
No coin nor oath required. For personal study only.
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A variety of compounds that show promise in cancer chemotherapy and chemoprevention have been identified as farnesyltransferase inhibitors. These can be classified into mainly two different types of inhibitors, farnesyl diphosphate competitors and CAAX peptidomimetics. The former type acts by compet
We have studied telomere length in the bone marrow cells or the granulocyte and lymphocyte cell fractions of 54 patients with myelodysplastic syndromes (MDS) by Southern blot hybridization using the (TTAGGG)4 probe. The average telomere length expressed as the peak telomere repeat array (TRA) in the