It is well-known that medullary thyroid carcinoma occurs in a familial form as part of the multiple endocrine neoplasia (MEN) 2 syndromes. However, it is less well-recognized that nonmedullary thyroid carcinoma (NMTC) sometimes is familial. Arising from the thyroid epithelial cell, the NMTCs include
Family with nonmedullary thyroid neoplasms
β Scribed by Kaoru Kobayashi; Yoshiyuki Tanaka; Shingo Ishiguro; Tohru Mori; Chiaki Shigemasa; Yasuo Mitani
- Book ID
- 102924315
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 554 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0022-4790
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β¦ Synopsis
This report concerns a family in which papillary thyroid carcinoma appeared in the father and two daughters and follicular adenoma in a granddaughter. The father died of systemic metastasis of papillary thyroid carcinoma. The two daughters and glanddaughter felt well postoperatively. We speculate that some gene-related factors might play an important role in familial occurrence of papillary thyroid carcinoma and follicular thyroid adenoma in the family.
π SIMILAR VOLUMES
Benign thyroid disease is a risk factor for nonmedullary thyroid carcinoma [Houlston and Stratton: Q J Med 88:685-693, 1995]. We report on a family with 7 members with benign and/or malignant thyroid neoplasia; one affected female died of a paravertebral alveolar rhabdomyosarcoma at age 20. The occu