𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Family-based association tests using genotype data with uncertainty

✍ Scribed by Yu, Z.


Book ID
111886786
Publisher
Oxford University Press
Year
2011
Tongue
English
Weight
221 KB
Volume
13
Category
Article
ISSN
1465-4644

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Tests for genetic association using fami
✍ Mei-Chiung Shih; Alice S. Whittemore πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 102 KB πŸ‘ 1 views

We use likelihood-based score statistics to test for association between a disease and a diallelic polymorphism, based on data from arbitrary types of nuclear families. The Nonfounder statistic extends the transmission disequilibrium test (TDT) to accommodate affected and unaffected offspring, missi

Exact family-based association tests for
✍ Kady Schneiter; Nan Laird; Chris Corcoran πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 134 KB πŸ‘ 1 views

## Abstract Family‐based study designs have an important role in the search for association between disease phenotypes and genetic markers. Unlike traditional case‐control methods, family‐based tests use within‐family data to avoid identification of spurious associations that may result from popula

Genetic association tests for family dat
✍ Alice S. Whittemore; Jerry Halpern πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 151 KB πŸ‘ 2 views

## Abstract We consider three tests for genetic association in data from nuclear families (the Family‐Based Association Test (FBAT) test proposed by Rabinowitz and Laird ([2000] Hum. Hered. 50:211–223), a second test proposed by Rabinowitz ([2002] J. Am. Stat. Assoc. 97:742–758), and the Family Gen

A general class of association tests for
✍ Xin Liu; Derek Gordon πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 190 KB πŸ‘ 1 views

## Abstract Based on the symmetry of transmitted/nontransmitted alleles from heterozygous parents under the null hypothesis of no association, the work proposed here establishes a general statistical framework for constructing association tests with data from nuclear families with multiple affected