Family-based association tests for quantitative traits using pooled DNA
โ Scribed by Bader, Joel S; Sham, Pak
- Book ID
- 110025313
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 167 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1018-4813
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## Abstract We present a class of familyโbased association tests (FBATs) for ordinal traits that adjust for the effects of covariates. For complex diseases, especially mental health conditions including nicotine dependence and substance use, the outcome variables are often recorded in an ordinal ra
## Abstract Association mapping based on family studies can identify genes that influence complex human traits while providing protection against population stratification. Because no gene is likely to have a very large effect on a complex trait, most family studies have limited power. Among the co