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Familial Thyroxin-Binding Globulin Deficiency

โœ Scribed by Kiyohiko Kato; Iwao Takakura; Yoshiki Kuno; Kazuo Ishikawa; Yasuo Ichihashi


Book ID
118709975
Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
297 KB
Volume
14
Category
Article
ISSN
1328-8067

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Sequence of the variant thyroxine-bindin
โœ Onno E. Janssen; Kyoko Takeda; Samuel Refetoff ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 446 KB

The variant thyroxine-binding globulin in a family from Montreal (TBG-M) has a reduced affinity for thyroxine, shows a slight cathodal shift on isoelectric focusing, and has an increased susceptibility to inactivation by heat and acid. We present the molecular basis for TBG-M, deduced by sequencing