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Familial Mediterranean Fever In Lebanon: Founder Effects For Different MEFV Mutations

✍ Scribed by Nadine Jalkh; Emmanuelle Génin; Eliane Chouery; Valérie Delague; Myrna Medlej-Hashim; Charles-Antoine Idrac; André Mégarbané; Jean-Louis Serre


Book ID
111111387
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
482 KB
Volume
0
Category
Article
ISSN
0003-4800

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Familial Mediterranean Fever (FMF) is a recessive inherited disorder affecting Sephardic Jews, Arabs, Armenians and Turks. The gene responsible for FMF was recently cloned and several disease-associated mutations have been described. We have evaluated seven MEFV mutations in 460 chromosomes of 230 u