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MEFV gene mutations in Iranian patients with familial mediterranean fever (FMF)

✍ Scribed by Mohammad Reza Zali; Seyed Javad Mirhassani Moghaddam; Farnaz Taghizadeh; Nastaran Noroozi; Akram Narimani; Sarvin Peyman; Faramarz Derakhshan

Book ID: 119394556
Publisher: Nature Publishing Group
Year: 2003
Tongue: English
Weight: 35 KB
Volume: 98
Category: Article
ISSN: 0002-9270
DOI: 10.1016/s0002-9270(03)00980-8

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Familial Mediterranean Fever (FMF) is a recessive inherited disorder affecting Sephardic Jews, Arabs, Armenians and Turks. The gene responsible for FMF was recently cloned and several disease-associated mutations have been described. We have evaluated seven MEFV mutations in 460 chromosomes of 230 u