𝔖 Bobbio Scriptorium
✦   LIBER   ✦

FAMILIAL MALE PSEUDOHERMAPHRODITISM DUE TO DEFICIENCY OF 5α-REDUCTASE

✍ Scribed by M. O. SAVAGE; M. A. PREECE; S. L. JEFFCOATE; P. G. RANSLEY; G. RUMSBY; M. D. MANSFIELD; D. I. WILLIAMS

Book ID
114717534
Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
936 KB
Volume
12
Category
Article
ISSN
0300-0664

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Male pseudohermaphroditism due to 5α-red
Male pseudohermaphroditism due to 5α-reductase deficiency in a Swedish family
✍ S. -A. Ivarsson; M. Damkjaer Nielsen; T. Lindberg 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 881 KB

Three sibs with an inherited form of male pseudohermaphroditism are described. They were all born with ambiguous external genitalia but no diagnosis of a possible enzyme defect was made during childhood. First seen at the ages of 16, 14 and 10 years respectively, they were investigated in order to e

Phenotypic classification of male pseudo
Phenotypic classification of male pseudohermaphroditism due to steroid 5α-reductase 2 deficiency
✍ Sinnecker, Gernot H. G.; Hiort, Olaf; Dibbelt, Leif; Albers, Norbert; Dörr, Helm 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 46 KB

Conversion of testosterone (T) to dihydrotestosterone (DHT) in genital tissue is catalysed by the enzyme 5a-reductase 2, which is encoded by the SRD5A2 gene. The potent androgen DHT is required for full masculinization of the external genitalia. Mutations of the SRD5A2 gene inhibit enzyme activity,