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Familial Down's syndrome A cytogenetical and genealogical study of twenty-two families

โœ Scribed by MARGARETA MIKKELSEN

Book ID
115247024
Publisher
John Wiley and Sons
Year
1966
Tongue
English
Weight
902 KB
Volume
30
Category
Article
ISSN
0003-4800

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We analyzed the possibility of inherited predisposition to nondisjunction in a family with two cases of Down syndrome using restriction fragment length polymorphisms and cytogenetic heteromorphisms. In both patients the extra chromosome 21 was the result of a nondisjunction event at first meiotic di