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Familial deficiency of the seventh component of complement associated with recurrent meningococcal infections

✍ Scribed by W. Nürnberger; H. Pietsch; R. Seger; T. Bufon; V. Wahn


Publisher
Springer
Year
1989
Tongue
English
Weight
437 KB
Volume
148
Category
Article
ISSN
0340-6997

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A C7 cDNA probe detecting a TaqI restriction fragment length polymorphism has been used to examine the segregation of the "silent allele" (C7\*Q0) in two familial deficiencies. Carrier diagnosis in healthy children is possible when both parents are heterozygotes. Only one of these two families was i