Mutation analysis of the adenomatous pol
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Clara Ruiz-Ponte; Ana Vega; Angel Carracedo; Francisco Barros
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Article
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2001
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John Wiley and Sons
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English
β 26 KB
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Germline mutations in the tumor-suppresor APC gene are associated with hereditary familial adenomatous polyposis (FAP) and somatic mutations are common in sporadic colorectal cancer. In this study, we report the identification of three novel germline mutations: 1682-1683insA, 3252-3253insAT, 3544A>T