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Familial adenomatous polyposis (FAP) and cancer

✍ Scribed by B.L. Bleau


Book ID
118526836
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
147 KB
Volume
41
Category
Article
ISSN
1097-6779

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Mutation analysis of the adenomatous pol
✍ Clara Ruiz-Ponte; Ana Vega; Angel Carracedo; Francisco Barros πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 26 KB πŸ‘ 2 views

Germline mutations in the tumor-suppresor APC gene are associated with hereditary familial adenomatous polyposis (FAP) and somatic mutations are common in sporadic colorectal cancer. In this study, we report the identification of three novel germline mutations: 1682-1683insA, 3252-3253insAT, 3544A>T