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False positives and false negatives: is the answer relatively simple?

✍ Scribed by Vella, S.; Pai, N.

Book ID
119825936
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
62 KB
Volume
127
Category
Article
ISSN
0001-690X

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This study examines the issue of false positives in genomic scans for detecting complex trait loci using sibpair linkage methods and investigates the trade-off between the rate of false positives and the rate of false negatives. It highlights the tremendous cost in terms of power brought about by an