𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Fall risk and gait in Parkinson's disease: The role of the LRRK2 G2019S mutation

✍ Scribed by Mirelman, Anat; Heman, Talia; Yasinovsky, Kira; Thaler, Avner; Gurevich, Tanya; Marder, Karen; Bressman, Susan; Bar-Shira, Anat; Orr-Urtreger, Avi; Giladi, Nir; Hausdorff, Jeffrey M.


Book ID
121397500
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
932 KB
Volume
28
Category
Article
ISSN
0885-3185

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


G2019S LRRK2 mutation in familial and sp
✍ Sofya N. Pchelina; Andrei F. Yakimovskii; Olga N. Ivanova; Anton K. Emelianov; A πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 80 KB

## Abstract Among mutations associated with autosomal dominant and sporadic Parkinson's disease (PD) the G2019S substitution in the leucine‐rich repeat kinase 2 (LRRK2) gene is the most frequently identified. To estimate its frequency in Russia, we analyzed 208 patients with PD from the Northwester

LRRK2 G2019S mutations are associated wi
✍ Rachel Saunders-Pullman; Matthew J. Barrett; Kaili M. Stanley; Marta San Luciano πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 70 KB

## Abstract Leucine rich repeat kinase (__LRRK2__) G2019S mutations are presumed to cause PD through a toxic gain of function of the protein kinase. Small molecule kinase inhibitors have been developed for the treatment of certain cancers, and some antioncogenic agents such as sunitinib, may nonspe