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Failure to detect nucleic acid homology between some non-A, Non-B viruses and hepatitis B virus DNA

✍ Scribed by M. J. F. Fowler; Dr. J. Monjardino; I. V. Weller; M. Bamber; P. Karayiannis; A. J. Zuckerman; H. C. Thomas

Publisher: John Wiley and Sons
Year: 1983
Tongue: English
Weight: 531 KB
Volume: 12
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890120306

No coin nor oath required. For personal study only.

✦ Synopsis

Some studies suggest that there is antigenic and nucleic acid homology of one type of non-A, non-B hepatitis virus with hepatitis B viral (HBV) proteins and DNA. Using molecular hybridization under high and low stringency conditions with high specific activity 32P-HBV DNA as a probe, serum and liver samples from patients and nonhuman primates infected with non-A, non-B hepatitis were examined. Our results provide no evidence of significant homology between the DNA extracted from serum and liver of patients and nonhuman primates infected with one type of non-A, non-B hepatitis and HBV DNA.

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