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Failure to demonstrate early metabolic changes in weanling growth-retarded hypophagic rats with lesions in the dorsomedial hypothalamic nuclei

✍ Scribed by Lee L. Bernardis; Marjorie Kodis; Geraldine McEwen

Book ID
118352391
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
918 KB
Volume
35
Category
Article
ISSN
0031-9384

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## Abstract Bilateral electrolytic lesions were placed in the dorsomedial hypothalamic nuclei (DMN) of weanling male Sprague‐Dawley rats. Sham‐operated rats served as controls. After 22 days on lab chow and tap water ad libitum, the animals were injected with U‐^14^ C‐alanine 0.167 μC/μ moles intra

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## Abstract Male rats received bilateral electrolytic lesions shortly after weaning in the ventromedial (VMN) and dorsomedial (DMN) hypothalamic nuclei, respectively. A third group of rats served as sham‐operated controls. The animals were subjected to intragastric preloading with 33% d‐glucose and