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Failure of L-NAME to cause inhibition of nitric oxide synthesis: Role of inducible nitric oxide synthase

✍ Scribed by M. J. S. Miller; J. H. Thompson; X. Liu; S. Eloby-Childress; H. Sadowska-Krowicka; X-Jing Zhang; D. A. Clark


Publisher
SP Birkhäuser Verlag Basel
Year
1996
Tongue
English
Weight
883 KB
Volume
45
Category
Article
ISSN
1420-908X

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The role of iNOS in rats after mild hemorrhaging was examined in this study. A mild hemorrhage (17% of total blood) induced a decrease of systemic blood pressure and heart rate, transiently followed by gradual recovery. The hemorrhage caused expression of renal iNOS mRNA and an increase in systemic