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FAF1, a Gene that Is Disrupted in Cleft Palate and Has Conserved Function in Zebrafish

✍ Scribed by Michella Ghassibe-Sabbagh; Laurence Desmyter; Tobias Langenberg; Filip Claes; Odile Boute; Bénédicte Bayet; Philippe Pellerin; Karlien Hermans; Liesbeth Backx; Maria Adela Mansilla; Sandra Imoehl; Stefanie Nowak; Kerstin U. Ludwig; Carlotta Baluardo; Melissa Ferrian; Peter A. Mossey; Markus Noethen; Mieke Dewerchin; Geneviève François; Nicole Revencu; Romain Vanwijck; Jacqueline Hecht; Elisabeth Mangold; Jeffrey Murray; Michele Rubini; Joris R. Vermeesch; Hélène A. Poirel; Peter Carmeliet; Miikka Vikkula

Book ID
113422982
Publisher
American Society of Human Genetics
Year
2011
Tongue
English
Weight
897 KB
Volume
88
Category
Article
ISSN
0002-9297

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Investigations of the genomic region that contains the clf1 mutation, a causal gene in multifactorial cleft lip and palate in mice
✍ Diana M. Juriloff; Muriel J. Harris; Sarah L. Dewell; Carolyn J. Brown; Dixie L. 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 261 KB 👁 2 views

## Abstract ## BACKGROUND Human nonsyndromic cleft lip and palate, CL(P), is genetically complex, with one contributing gene on chromosome 17q. A potentially homologous gene, __clf1__ on distal chromosome 11, is part of the digenic cause of the 10–30% CL(P) in the A/WySn mouse strain. Here we repo