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Factors influencing articular cartilage wear in vitro

✍ Scribed by Eric L. Radin; David A. Swann; Igor L. Paul; Paul J. Mcgrath

Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
733 KB
Volume
25
Category
Article
ISSN
0004-3591

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The in vitro wear of articular cartilage in oscillating and impulsively loaded bovine metatarsophalangeal joints was studied. Articular cartilage scarification had little effect on cartilage wear, but stiffening of the subchondral bone with methyl methacrylate greatly increased the rate of cartilage loss, whether or not it had previously been scarified. Glutaraldehyde treatment of articular cartilage for 30 minutes decreased its wear rate. Guanidinium chloride extraction of the cartilage before wear testing caused it to peel off its subchondral bed. This effect could be spared by prior glutaraldehyde fixation.

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