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Factors Governing the Instability of a Carbon to Nitrogen Bond. I. The Instability of the Carbon to Nitrogen Bond in Substituted Methyl Amines 1

โœ Scribed by Kharasch, M. S.; Howard, Louis B.


Book ID
125951508
Publisher
American Chemical Society
Year
1934
Tongue
English
Weight
451 KB
Volume
56
Category
Article
ISSN
0002-7863

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Asymmetric synthesis of ฮฑ-substituted am
โœ Kolb, Michael ;Barth, Jacqueline ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 1015 KB

## Abstract The asymmetric synthesis of ฮฑโ€substituted ฮฑโ€amino acids and propargylamines is described. As chiral auxiliary we used (__S__)โ€(โ€“)โ€1โ€dimethoxymethylโ€2โ€methoxymethylpyrrolidine (SDMP, **1**). Treatment of the amino acids or amines with SDMP **1** afforded the corresponding amidines **C**,