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Factors governing diffusing molecular signals in brain extracellular space

✍ Scribed by C. Nicholson

Book ID
106206735
Publisher
Springer
Year
2004
Tongue
English
Weight
172 KB
Volume
112
Category
Article
ISSN
1435-1463

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πŸ“œ SIMILAR VOLUMES

Maximum geometrical hindrance to diffusi
Maximum geometrical hindrance to diffusion in brain extracellular space surrounding uniformly spaced convex cells
✍ L Tao; C Nicholson πŸ“‚ Article πŸ“… 2004 πŸ› Elsevier Science 🌐 English βš– 719 KB

Brain extracellular space (ECS) constitutes a porous medium in which diffusion is subject to hindrance, described by tortuosity, lambda = (D/D\*)1/2, where D is the free diffusion coefficient and D\* is the effective diffusion coefficient in brain. Experiments show that lambda is typically 1.6 in no