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Factors effecting the induction of bacterial mutations by dimethylnitrosamine in mice

✍ Scribed by S. Neale; A.K. Solt

Book ID
113136124
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
368 KB
Volume
31
Category
Article
ISSN
0009-2797

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Induction of dominant lethal mutations i
Induction of dominant lethal mutations in male mice by fosfestrol
✍ U. H. Ehling πŸ“‚ Article πŸ“… 1978 πŸ› Springer-Verlag 🌐 English βš– 342 KB

Using the dominant lethal assay, the ability of fosfestrol, a diethylstilboestrol derivate, to induce mutations in male mice was tested and confirmed. Up to 300 mg/kg of fosfestrol the induction of mutations occurs exclusively in spermatozoa. A dose of 600 mg/kg of fosfestrol induces dominant lethal