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Factors affecting sensitivity to antitumor platinum derivatives of human colorectal tumor cell lines

โœ Scribed by Noriaki Kitada; Kohji Takara; Tetsuya Minegaki; Chihiro Itoh; Masayuki Tsujimoto; Toshiyuki Sakaeda; Teruyoshi Yokoyama


Publisher
Springer
Year
2007
Tongue
English
Weight
317 KB
Volume
62
Category
Article
ISSN
0344-5704

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L1210 leukemia cells, because of their rapid growth rate in suspension culture and high growth fraction, are ideally suited to screen in vitro for cytotoxic compounds. Although L1210 cells may mimic rapidly growing tumors, they have not been effective in selecting agents active against slow growing