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Factor VIII-specific memory B cells in patients with hemophilia A

✍ Scribed by P. M. W. VAN HELDEN; P. H. P. KAIJEN; K. FIJNVANDRAAT; H. M. VAN DEN BERG; J. VOORBERG

Book ID: 109152299
Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 158 KB
Volume: 5
Category: Article
ISSN: 1538-7933
DOI: 10.1111/j.1538-7836.2007.02736.x

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Hemophilia A is a common X-linked bleeding disorder caused by mutations in the coagulation factor VIII gene. The entire coding and essential sequences of the factor VIII gene were generated by a combination of genomic DNA amplification and long reverse transcription-polymerase chain reaction (long R