Modified APC-resistance test: Variable r
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Ts'ao, Chung-hsin; Neofotistos, Demetra; Oropeza, Maria; Vahabinejad, Shahla; Fi
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Article
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1997
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John Wiley and Sons
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English
⚖ 69 KB
A single point mutation of the factor V (FV) gene, leading to the substitution Arg506Gln in the FV molecule (FV-Leiden) and hence resistance to its breakdown by activated protein C (APC), is the most prevalent risk factor for venous thrombosis in the Caucasians. A ratio determined by activated parti