Developmental status of CD4–CD8+ and CD4
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Michael A. Sheard; Cunlan Liu; Yousuke Takahama
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Article
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2004
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John Wiley and Sons
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English
⚖ 568 KB
## Abstract In normal mice, more than 10% of thymocytes in the CD4^+^CD8^–^ and CD4^–^CD8^+^ single‐positive (SP) subsets express a medium level of CD3 on the cell surface. However, the fate of CD3^medium^ cells is unclear. The CD3^medium^ SP subpopulations might contain (i) cells in an immature st