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FACILE THIOLYTIC REMOVAL OF THE o-NITROPHENYLSULPHENYL AMINO-PROTECTING GROUP

โœ Scribed by STERN, MEIR ;WARSHAWSKY, ABRAHAM ;FRIDKIN, MATI


Book ID
115097497
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
403 KB
Volume
13
Category
Article
ISSN
0367-8377

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โœ Aung Tun-Kyi ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› John Wiley and Sons ๐ŸŒ German โš– 304 KB

## Abstract 2โ€Thiopyridone (2โ€mercaptopyridine, **1**) was found to be a very suitable reagent for removing the __N__^ฮฑ^โ€oโ€nitrophenylsulfenyl (NPSโ€) group in both conventional and solidโ€support peptide synthesis. A 3โ€ to 5โ€molar excess of the reagent together with an equivalent amount of glacial a