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Facile synthesis of α-difluoromethyl α-propargylamines from CF2H-substituted N-tert-butanesulfinyl ketimines

✍ Scribed by Hui Chen; Wei Yu; Xin Hua Guo; Wei Dong Meng; Yan Gen Huang


Book ID
113523305
Publisher
Chinese Electronic Periodical Services
Year
2012
Tongue
English
Weight
226 KB
Volume
23
Category
Article
ISSN
1001-8417

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## Abstract The first highly efficient and stereoselective difluoromethylation of structurally diverse __N‐tert__‐butylsulfinyl ketimines has been achieved with an in situ generated PhSO~2~CF~2~^−^ anion, which provides a powerful synthetic method for the preparation of a variety of structurally di