✦ LIBER ✦

Facile synthesis of novel fluorescent distamycin analogues

✍ Scribed by Santanu Bhattacharya; Mini Thomas

Publisher: Elsevier Science
Year: 2001
Tongue: French
Weight: 200 KB
Volume: 42
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)01040-1

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✦ Synopsis

A facile synthesis of four distamycin analogues that bear the dansyl fluorophore is described. The nature of the linkage between the fluorophore and the sequence recognition element had a dramatic effect on the fluorescence properties of these ligands upon DNA binding.

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